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Musi wa8 Gumiguru, timu yekutsvagisa kubva kuSchool OF Pharmacy yeZHONGSHAN University yakaburitsa bepa muARCHIVES OF TOXICOLOGY, iro repakati rejenari repasi rose toxicology, richiratidza kuti panguva imwecheteyo nicotine dose, e-fodya sol haina kukuvadza kukufema. system pane yefodyafodya.

Mumakore achangopfuura, migumisiro yehutano ye-e-cigarettes uye fodya yave ichikakavadzana zvakanyanya mumunda wehutano hwevanhu.Muchidzidzo ichi, chikwata cheZHONGSHAN University tsvakurudzo chakaenzanisa migumisiro yefodya uye e-fodya pakushanda kwemapapu, zvinhu zvinoputika uye mapuroteni ekutaura mumakonzo ane chikakananda chakafanana, icho chakazadza gaka rekutsvakurudza kwesayenzi mundima dzine hukama.

Vatsvakurudzi vakashandisa RELX watermelonflavouted e-cigarettesuye fodya yechinyakare semasampuli, huwandu hwe32 mbeva dzakakamurwa zvisina tsarukano mumapoka e4 uye dzakafumurwa kumhepo yakachena, yakaderera dose e-cigarette sol, yakanyanya dose e-cigarette sol uye utsi hwefodya kwemavhiki e10, uye indexes yavo yakaongororwa.

Mhedzisiro yemapapu histopathology yakaratidza kuti mapapu coefficient yemakonzo akafumurwa mudzanga akawedzera zvakanyanya, uye morphology yetrachea yakachinja, zvichiratidza kuti nzira yekufema inogona kurwara.Kuenzanisa, pakanga pasina shanduko yakakosha mumapapu coefficient uye trachea morphology mumakonzo akaiswa kune e-cigarettes.

Miedzo yebasa remapapu yakaratidza kuti kufumurwa kwefodya kwakakonzera kukanganisa kwakanyanya mune akati wandei emapapu ekushanda indekisi mumakonzo, asi indekisi imwe chete yakadzikira muboka re-e-cigarette.Panguva imwecheteyo, mhedzisiro yehutachiona yakaratidza kuti zvese fodya uye e-fodya zvinogona kukonzera kusakwana kwemapapu mumakonzo, asi kukuvadzwa kwakakonzerwa nefodya kwainyanya kuoneka.

Pakupedzisira, muongorori akaitawo proteomic ongororo yembeva yemapapu tishu.Zvigumisiro zvakaratidza kuti mapuroteni akasiyana-siyana anokonzerwa nefodya akanga akanyanya kunyanya kuvhiringidza nzira dzine chokuita nekuputika, nepo kutaura kusina kujairika kwakakonzerwa nefodya kwakanga kuri kushoma, uye mhedzisiro panzira yekuratidzira yekuzvimba yaive diki.

Vatsvagiri vanoti mhedzisiro yacho inoratidza pachena kuti kufumurwa kune yakakura inhaled doses yefodya uye e fodya inokuvadza kumweya wekufema.Nekudaro, pasi pechikakana chimwe chete, e-cigarette sol haina kukuvadza kuhurongwa hwekufema kupfuura utsi hwechinyakare hwefodya.

Vaping inoonekwa zvakanyanya nevekurapa seimwe nzira isingakuvadze nekuti haiburitse tara uye haidi kupiswa.