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Ongororo yazvino yakaburitswa neCanada sainzi timu yekutsvagisa inoratidza kuti cannabinoids inogona kuita basa mukudzivirira nekurapa COVID-19 uye kwenguva refu COVID.

Mukuwongorora kwakadzama, boka revasaenzi veCanada rinopa maonero anonakidza mune rinogona kuita basa re cannabinoids mukurwisa hutachiona hweCOVID-19.Chidzidzo ichi, chakanzi "Cannabinoids uye Endocannabinoid System in Early SARS-CoV-2 uye Chronic COVID-19 Varwere," yakanyorwa naCassidy Scott, Stefan Hall, Juan Zhou, Christian Lehmann nevamwe uye yakaburitswa muChinyorwa cheSARS-CoV. -2″ magazini.

Clinical Medicine.Nekuongorora data rakawanda kubva kuzvidzidzo zvekare, chirevo chinokurukura kuti zvikamu zvechirimwa che cannabis zvinogona kuita basa rakakosha kudzivirira kutanga kweCCIDID-19 uye kudzikisira mhedzisiro yayo yenguva refu.Zvakawanikwa zvinoratidza kuti cannabinoids, kunyanya iyo yakatorwa kubva muchirimwa che cannabis, inogona kutadzisa hutachiona kupinda mumasero, kuderedza inokuvadza oxidative kusagadzikana, uye kudzvinyirira kazhinji inouraya immune system inoonekwa mumatambudziko akaomarara.Chidzidzo ichi zvakare chinosimbisa iro rinogona kuita basa re cannabinoids mukugadzirisa zvakasiyana-siyana zvinoramba zvichiitika zvenguva refu COVID-19.

Sekureva kwechidzidzo ichi, cannabinoids ine mukana mukudzivirira kupinda kwehutachiona, kuderedza oxidative kusagadzikana uye kudzikisira dutu recytokine rakabatana nehutachiona hweCOVID-19.Tsvagiridzo inoratidza izvo chaizvocannabinoid zvinyorwainogona kudzikisira mazinga eangiotensin-inoshandura enzyme 2 (ACE2) mumatishu akakosha, nekudaro kudzivirira hutachiona kupinda mumasero emunhu.Vatsvagiri vanoona kuti izvi zvakakosha kupihwa basa reACE2 segedhi rekutanga rekupinda kwehutachiona.Chirevo ichi chinokurukurawo nezve basa re cannabinoids mukugadzirisa oxidative kusagadzikana, chinhu chakakosha pathogenesis yeCOVID-19.

Nekushandura mahara radicals kuita mashoma ekuita mafomu, cannabinoids akadaiCBDinogona kubatsira kudzikisira zvinokuvadza zvinokonzerwa neoxidative kusagadzikana mune dzakakomba nyaya dzeCOVID-19.Sekureva kwechidzidzo ichi, cannabinoids inogona zvakare kuve nemhedzisiro inobatsira pamadutu ecytokine, iyo yakasimba immune immune yakakonzerwa neCOVID-19.Cannabinoids yakaratidzwa kuva inoshanda mukuderedza cytokines inozvimba, zvichiratidza kugona kwavo mukugadzirisa mhinduro dzekudzivirira kwezvirwere zvakadaro.

Yakareba COVID inoreva mamiriro ayo anowanzoitika seCCIDID-19 shanduko kuenda kuchikamu chisingaperi.Tsvagiridzo inoratidza kugona kwe cannabinoids mukurapa zviratidzo zvinoramba zvichiitika zvekuora mwoyo, kuzvidya mwoyo, post-traumatic stress disorder, kushaya hope, kurwadziwa uye kurasikirwa kwechido.Iyo endocannabinoid sisitimu inoita basa mukudyidzana kweakasiyana masisitimu etsinga, zvichiita kuti ive chinangwa chekurapa kweizvi neuropsychiatric zviratidzo.

Chidzidzo ichi chakaongororawo nzira dzakasiyana dzekushandisa uye marudzi akasiyana ezvigadzirwa zve cannabis zvinoshandiswa nevatengi.Tsvagiridzo inoratidza kuti kupinza kuburikidza nekufemerwa kunogona kuve nemhedzisiro yakaipa kune vanhu vane mamiriro ekufema, zvinopesana nemhedzisiro yayo yekurapa."Kunyange kusvuta uye kuputa kunowanzova nzira dzinofarirwa nevarwere vecannabis nekuti ivo vane kukurumidza kuita kwekuita, mabhenefiti angangoita e cannabinoid kurapwa anogona kuderedzwa neakaipa mhedzisiro yekufema pahutano hwekufema," vaongorori vakadaro.Kudzidza Kunoratidza "Varwere vanoshandisa cannabis vaporization vanoona zvishoma zviratidzo zvekufema pane kuputa nekuti mudziyo wevaporizer haupise cannabis kusvika pakupisa."Vanyori vemushumo vanosimbisa kudiwa kweimwe ongororo munzvimbo iyi.Kunyange izvo zvekutanga zvakawanikwa zvichikurudzira, vanoyambira kuti ndezvekutanga uye zvinobva muzvidzidzo zvisina kunangana neCOVID-19.Naizvozvo, zvidzidzo zvakanangwa uye zvakazara, kusanganisira miedzo yekiriniki, zvakakosha kuti unzwisise zvizere basa uye kushanda kwe cannabinoids mukurapa kwekutanga uye kwakaoma chikamu cheSARS-CoV-2 chirwere.Uyezve, vanyori vanotsigira kutsvakurudza kwakadzama mu pharmacology uye zvinogona kurapa zvikumbiro zve endocannabinoid system uye vanokurudzira nharaunda yesainzi kuti iongorore zvine hungwaru nzira iyi.